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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC12A2 All Species: 8.74
Human Site: T6 Identified Species: 21.37
UniProt: P55011 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55011 NP_001037.1 1212 131447 T6 _ _ M E P R P T A P S S G A P
Chimpanzee Pan troglodytes XP_526998 1211 131461 T6 _ _ M E P R P T A P S S G A P
Rhesus Macaque Macaca mulatta XP_001098624 1210 131015 T6 _ _ M E P V P T A P S S G A P
Dog Lupus familis XP_538611 1263 138005 L61 R R P P Q R R L R G N P A S P
Cat Felis silvestris
Mouse Mus musculus P55012 1205 130932 L10 P G P A G P R L A P A A R P G
Rat Rattus norvegicus P55016 1095 120578 P6 _ _ M S V N I P S N S V P S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413814 1097 121884 P7 _ M S M N N S P N V F L D P N
Frog Xenopus laevis Q0VGW6 899 98326
Zebra Danio Brachydanio rerio A2BFP5 899 98457
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34261 903 100556
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 87.5 N.A. 92.7 57.6 N.A. N.A. 57.6 22.9 21.7 N.A. N.A. N.A. 23.4 N.A.
Protein Similarity: 100 99.8 99.1 90 N.A. 94.3 71.3 N.A. N.A. 70 39 39.8 N.A. N.A. N.A. 40.2 N.A.
P-Site Identity: 100 100 92.3 13.3 N.A. 13.3 15.3 N.A. N.A. 0 0 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 92.3 26.6 N.A. 33.3 30.7 N.A. N.A. 0 0 0 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 40 0 10 10 10 30 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 0 0 0 10 0 0 30 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 20 0 0 0 10 0 0 0 % L
% Met: 0 10 40 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 20 0 0 10 10 10 0 0 0 10 % N
% Pro: 10 0 20 10 30 10 30 20 0 40 0 10 10 20 40 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 10 0 0 0 30 20 0 10 0 0 0 10 0 0 % R
% Ser: 0 0 10 10 0 0 10 0 10 0 40 30 0 20 0 % S
% Thr: 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 10 0 0 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 50 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % _